Magnesium deficiency and its potential link to Inflammation

The study below briefly discusses the importance of having the right levels of magnesium and the potential systemic health concerns of being deficient for yourself and for your patients. Also, did you know that Epsom salt is made up of magnesium sulfate? Read below . . .

Dietary magnesium and C-reactive protein levels.

King DE, Mainous AG 3rd, Geesey ME, Woolson RF

Department of Family Medicine, Medical University of South Carolina, 295 Calhoun Street, PO Box 250192, Charleston, SC 29425, USA.



Current dietary guidelines recommend adequate intake of magnesium (310–420 mg daily) in order to maintain health and lower the risk of cardiovascular disease. Recent evidence from animal and clinical studies suggests that magnesium may be associated with inflammatory processes. The objective of this study was to determine whether dietary magnesium consumption is associated with C-reactive protein (CRP), a marker of inflammation, in a nationally representative sample.


Analysis of adult (> or =17 years) participants in a cross-sectional nationally representative survey (National Health and Nutrition Examination Survey 1999-2000 [NHANES]) who were not taking magnesium or magnesium-containing supplements. The primary outcome measure was high sensitivity CRP (elevated > or =3.0 mg/L).


Among U.S. adults, 68% consumed less than the recommended daily allowance (RDA) of magnesium, and 19% consumed less than 50% of the RDA. After controlling for demographic and cardiovascular risk factors, adults who consumed <RDA of magnesium were 1.48–1.75 times more likely to have elevated CRP than adults who consumed > or =RDA (Odds Ratio [OR] for intake <50% RDA = 1.75, 95% Confidence Interval [CI] 1.08–2.87). Adults who were over age 40 with a BMI >25 and who consumed <50% RDA for magnesium were 2.24 times more likely to have elevated CRP (95% CI 1.13–4.46) than adults > or =RDA.


Most Americans consume magnesium at levels below the RDA. Individuals with intakes below the RDA are more likely to have elevated CRP, which may contribute to cardiovascular disease risk.

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What’s in Epsom Salt and How It Works

Most people know about the importance of calcium and vitamin D, but many Americans are also magnesium deficient. Doctors say it stems largely from the increasing prevalence of processed foods in our diets. Today, 68 percent of U.S. adults consume less than the recommended daily allowance (RDA) of magnesium, according to the study above, and 19 percent consume less than half the RDA.

Epsom salt is made of naturally occurring minerals magnesium and sulfate, ingredients that can help improve health in numerous ways. A lack of magnesium—which helps regulate the activity of more than 300 enzymes in the body—can contribute to high blood pressure, hyperactivity, heart problems, and other health issues, doctors warn. Sulfate is essential for many biological processes, helping to flush toxins and form proteins in joints, brain tissue, and mucin proteins.

The Health Benefits of Absorbing Magnesium, Sulfate Through the Skin

The benefits of Epsom salt aren’t just folklore. In fact, numerous studies have demonstrated the profound and wide-ranging benefits of magnesium and sulfate. Doctors and researchers say that when you soak in an Epsom salt bath, magnesium and sulfate can be absorbed through the skin. They recommend an Epsom salt bath as a safe, easy way to increase the body’s levels of both magnesium and sulfate.

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